Wegovy First Month Results: What To Expect
Wegovy is one of the most trending weight loss medications currently available in the UK. Clinical trials have reported an average weight loss of 17% over 68 weeks using the once-weekly weight loss injection.
Most of the weight loss occurs in the first 9 months of use. Here, we’ll explore what you can expect during your first month's use and beyond.
How Does Wegovy Work? A Quick Recap
Originally developed for type 2 diabetes, GLP-1 receptor agonists, which include Wegovy (semaglutide), have been shown to aid in weight loss by influencing hunger and digestion.
In a nutshell, Wegovy works by mimicking natural hormones that regulate appetite and metabolism, leading to:
- Less frequent cravings and better appetite control
- Slower digestion, helping you feel full longer
- Improved blood sugar regulation, which supports weight management
Weight loss medications such as Wegovy do not totally replace healthy habits, which support and accelerate progress. However, they can make it far easier to stay on track while encouraging long-term weight loss.
Wegovy Before and After
Now, let’s take a glance through ten real stories from people who committed to weight loss with Wegovy – and experienced great results.
User 1: 152 Pounds (68.9 kg) Lost and Still Making Progress
- Starting Weight: 244 lbs (110.7 kg)
- Current Weight: 166 lbs (75.3 kg)
- New Goal Weight: 150 lbs (68.0 kg)
- Total Weight Loss: 152 lbs (68.9 kg)
This user started their Wegovy journey at 244 lbs (110.7 kg) after previously reaching a high of 318 lbs (144.2 kg).
Over time, they successfully dropped down to 166 lbs (75.3 kg), surpassing their initial weight loss goal – meaning they had to set a new lower objective.
After increasing their dosage, they noticed some weight fluctuation but remained unconcerned. Their excellent progress proves that patience and consistency pay off in the long run, despite speed-bumps.
User 2: 77 Pounds (34.9 kg) Gone – A Whole New Fit
- Starting Weight: 264 lbs (119.7 kg)
- Current Weight: 187 lbs (84.8 kg)
- Goal Weight: 150 lbs (68 kg)
- Dosage: Wegovy 2.4mg
- Total Weight Loss: 77 lbs (34.9 kg)
This user has lost 77 pounds (34.9 kg) since starting Wegovy, going from 264 lbs (119.7 kg) to 187 lbs (84.8 kg).
Working in a medical office, they’ve received numerous compliments about their strong progress.
User 3: 99 Pounds (44.9 kg) Down – Life Completely Transformed
- Starting Weight: 213 lbs (96.6 kg)
- Current Weight: 134.8 lbs (61.1 kg)
- Goal Weight: 135 lbs (61.2 kg)
- Dosage: Wegovy 2.4 mg
- Total Weight Loss: 99 lbs (44.9 kg)
It’s been a long road, but this user’s life is completely different from when they first decided to lose weight. Despite major life changes – including becoming a widow and moving house – they stuck to their plan.
One key lesson is that these medications are not an "easy fix," but they can be an incredible tool when combined with a commitment to health and self-care.
If you’re considering Wegovy, you’ll need a prescription. Start your consultation today with a licensed provider.
User 4: 100 Pounds (45.4 kg) in One Year
- Starting Weight: 290 lbs (131.5 kg)
- Current Weight: 190 lbs (86.2 kg)
- Time Using Wegovy: 1 year
- Total Weight Loss: 100 lbs (45.4 kg)
This user has officially hit 100 pounds (45.4 kg) down after 365 days of progress – a full year of dedication with absolute commitment to their fitness goals.
Over the past year, they’ve comprehensively changed their lifestyle, finding joy in movement and pushing themselves beyond their limits. They’re much fitter now and more confident with pursuing physical activity.
User 5: 80 Pounds (36.3 kg) Down and Feeling Like Themselves Again
- Starting Weight: 250 lbs (113.4 kg)
- Current Weight: 170 lbs (77.1 kg)
- Time Using Wegovy: 10 months
- Total Weight Loss: 80 lbs (36.3 kg)
After 10 months on Wegovy, this user successfully lost 80 pounds (36.3 kg), going from 250 lbs (113.4 kg) to 170 lbs (77.1 kg).
Even more impressive? They’ve been off the medication for two months and have continued losing weight, albeit at a slower pace.
Reaching their goal weight successfully, they now feel great in their body again and are enjoying physical activity and sports.
User 6: 80 Pounds (36.3 kg) Gone and Counting
- Starting Weight: 200 lbs (90.7 kg)
- Current Weight: 120 lbs (54.4 kg)
- Time Using Wegovy: Not specified
- Dosage: Maintaining on 1 mg
- Total Weight Loss: 80 lbs (36.3 kg)
After a period of rapid weight loss, this user is now in maintenance mode, keeping their weight between 118–126 lbs (53.5–57.1 kg) while continuing 1 mg of Wegovy. They no longer want to lose more weight and are focusing on stability.
Moreover, they found their menstrual cycle was better-regulated after struggling with PCOS.
While they experienced temporary hair thinning, they believe it was due to either rapid weight loss or hormonal shifts, but the issue has since resolved.
Thinking about adding Wegovy to your weight loss process? Our licensed providers can assess if it’s right for you – complete your consultation today.
User 7: 55 Pounds (24.9 kg) Down in 5 Months
- Starting Weight: 245 lbs (111.1 kg)
- Current Weight: 190 lbs (86.2 kg)
- Time Using Wegovy: 5 months
- Total Weight Loss: 55 lbs (24.9 kg)
This user started Wegovy at 245 lbs (111.1 kg) and has since lost 55 pounds (24.9 kg), bringing their weight down to 190 lbs (86.2 kg) in just five months.
That’s an incredible amount of weight loss in just 5 months and major progress towards their goal.
User 8: 63 Pounds (28.6 kg) Down – Nearing the Finish Line
- Starting Weight: 222.8 lbs (101.1 kg)
- Current Weight: 159.9 lbs (72.5 kg)
- Goal Weight: 148 lbs (67.1 kg)
- Dosage: 1 mg (never increased)
- Total Weight Loss: 63 lbs (28.6 kg)
Since starting Wegovy, this user has lost nearly 63 pounds (28.6 kg), bringing their weight down to 159.9 lbs (72.5 kg) and into the normal BMI range.
They pushed themselves hard, running 25 miles per week since September, which helped them consistently lose about 10 pounds per month.
With only about 12 pounds to go to strike their goal, they’re excited to complete their weight loss process.
User 9: 75 Pounds (34 kg) Lost – A Journey of Ups and Downs
- Starting Weight: 285 lbs (129.3 kg)
- Current Weight: 210 lbs (95.3 kg)
- Height: 5’4” (162.6 cm)
- Dosage: 2.4 mg
- Total Weight Loss: 75 lbs (34 kg)
This user’s weight loss wasn't completely straightforward before starting Wegovy as they struggled with yo-yoing weight loss and weight gain.
Once they got started on Wegovy, they dropped 75 pounds (34 kg), going from 285 lbs (129.3 kg) to 210 lbs (95.3 kg).
This involved adding more protein, fibre, healthy fats, and vegetables to their diet and upping hydration levels, especially on days when eating was difficult.
For exercise, they kept it simple – walking 2-3 miles a day and adding more general movement into their daily routine.
User 10: 90 Pounds (40.8 kg) Down – A One-Year Transformation
- Starting Weight: 218 lbs (98.9 kg)
- Current Weight: 128 lbs (58.1 kg)
- Time Using Medication: Around one year
- Dosage: Not specified
- Total Weight Loss: 90 lbs (40.8 kg)
This user’s journey has been nothing short of life-changing. At 218 lbs (98.9 kg), simple tasks like climbing stairs required stopping to catch their breath. Running and playing with their child felt harder and harder.
Now, at 128 lbs (58.1 kg), they’ve flipped that on its head. They work out 3–6 times per week, eat in moderation, and can run and play with their son without limitations.
User 11:
First-month Wegovy results of a user who started with the 0.25 mg dose: Starting weight 183 lbs, current weight 170.9 lbs
User 12:
The following user lost 70 lbs in 9 months, starting at 198 lbs and now weighing 128 lbs. The user is currently on a maintenance dose of 0.5 mg.
What is Wegovy?
Wegovy is a self-injectable weight loss injection that contains the active ingredient semaglutide. It is used once a week and is most effective when used alongside a diet and exercise plan.
Semaglutide (Wegovy) works by mimicking a naturally produced hormone to curb your appetite and help you feel full after eating, lowering your calorie intake and promoting weight loss.
Wegovy is a prescription-only medication. You must meet certain criteria to qualify for Wegovy weight loss treatment and acquire a private prescription from one of the clinicians at Prescription Doctor.
Wegovy
- Approved Weight Loss treatment
- Weekly injection
- Reduces risk of heart attack & stroke
What To Expect From Wegovy In the First Month
Wegovy dosage schedule
Wegovy is available in 5 doses, starting with the lowest dose of 0.25 mg per week titrating up to the maximum dose of 2.4 mg per week.
Everyone begins Wegovy treatment on the lowest dose and makes their way up to the maximum or most tolerated dose. This dosage schedule helps your body get used to the new medication and limits side effects.
The Wegovy dosage schedule is shown below:
The different doses are supplied in a different coloured pen.
| Dose | Pen colour |
|---|---|
| 0.25 mg | Green |
| 0.5 mg | Pink |
| 1 mg | Brown |
| 1.7 mg | Blue |
| 2.4 mg | Black |
Wegovy
- Approved Weight Loss treatment
- Weekly injection
- Reduces risk of heart attack & stroke
How much weight can you lose after one month with Wegovy?
The STEP 1 clinical trial shows that the average weight loss after four weeks of Wegovy injections was around 2%. The data shows that after eight weeks the average weight loss was 4% (pink line), and 6% after 12 weeks (brown line).
Although this is a steady and increasing level of weight loss. It is clear that the effects of Wegovy are greater after 12 weeks, as the higher doses of 1.7 mg and 2.4 mg are reached.
Another randomised clinical controlled trial showed that the average body weight change from the start of the trial after four weeks of Wegovy use was 5%.
The data from this study also shows the average weight loss at:
- 8 weeks was 8%
- 12 weeks was 10%
Therefore, based on these studies, most people can expect to lose between 2 and 5% of their body weight in the first month.
Common Wegovy side effects
Alongside weight loss in the first month of taking Wegovy, some people may experience side effects.
Wegovy side effects may be most noticeable during the first month of treatment as your body gets used to the new medication.
Common Wegovy side effects include:
- feeling sick (nausea)
- being sick (vomiting)
- diarrhoea
- stomach pain
- headache
- tiredness/fatigue
- upset stomach
- dizziness
- bloating
- gas
- runny nose
- sore throat
The side effects are usually mild and reduce in severity over time as your body gets used to Wegovy. You can find out more about the side effects of Wegovy and how long they may last by reading our blog.
What are the long-term weight loss expectations?
Across both of the above studies, the weight loss across 68 weeks was significant with Wegovy. In the STEP 1 trial, after 68 weeks the average weight loss was 14.9% compared to 16% in the study published in JAMA.
A further clinical trial called SELECT found that Wegovy (semaglutide) produced clinically significant weight loss after 208 weeks. The study involved 17,604 patients and the average weight loss was 10.2% until week 65 where it then remained steady (plateaued) until week 208.
Long-term data shows that the average weight loss with Wegovy is between 10 and 16%.
Set realistic goals for long-term weight loss goals
When you first start Wegovy treatment, it is important to set realistic weight loss goals. You should focus on what you want to achieve long-term rather than opting for a quick weight loss fix. For example, you may want to lose a specific amount of weight before a wedding in two years time or fit in a certain-sized pair of jeans within a year.
Keep a diary of your weight loss journey to help you identify the small milestones you have achieved on your way to reaching your overall goal.
Lifestyle factors that affect Wegovy results
You are likely to see the best results when you combine Wegovy with a diet and exercise plan. The active ingredient, semaglutide, works best when it is combined with a low-calorie diet and regular exercise.
In the STEP 1 clinical trial, the average weight loss of 68 weeks was almost 15% but this wasn’t achieved with weekly Wegovy injections alone. As part of the treatment, participants receive counselling sessions every four weeks to help them stick to a reduced calorie diet and an increased level of exercise (150 minutes per week).
When you embark on your Wegovy weight loss journey, it’s important to follow a healthy, balanced diet that’s packed with natural foods like fruit, vegetables, and whole grains. By reducing the number of calories you eat and increasing your exercise levels, you’ll be proactively supporting your weight loss journey.
Making these lifestyle changes will not only help you get the most out of Wegovy but they will also help to enhance your mood and outlook, and stop you from regaining weight when you stop using Wegovy.
Mounjaro vs Wegovy: A Comprehensive Comparison
For a detailed look at how Wegovy compares with another popular weight loss medication, Mounjaro, visit our comprehensive guide: Mounjaro vs Wegovy: A Comprehensive Comparison. This information will help you understand the differences and similarities between the two treatments.
Conclusion
Starting your weight loss journey with Wegovy demonstrates your commitment to your health. You may notice that you have lost a small amount of weight during your first month's treatment and this can be good motivation. Some people may also experience subtle side effects during this time, but there are things you can do to help manage them as your body adjusts to Wegovy.
You can buy Wegovy online from Prescription Doctor. Start your consultation with one of our clinicians today.
Sources
NEJM, 2021. Once-Weekly Semaglutide in Adults with Overweight or Obesity.
Novo Nordisk, 2024. Common Side Effects of Wegovy.
Additional Resources
Authored By
Leanne Edermaniger
Medical Content WriterPublished on: 31/07/2024
Reviewed By
Mohamed Imran Lakhi
MPharm - Lead PharmacistReviewed on: 07/03/2025
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