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This is why we also take steps to conceal your prescription products under two layers of packaging.
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We deliver medications between Monday and Saturday. You can upgrade to Saturday delivery on Friday.
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Mounjaro contains the active ingredient tirzepatide and is manufactured and licensed by Eli Lilly. It is supplied as the KwikPen, a multi-dose prefilled injection device containing four weekly doses per pen.
Originally developed to treat type 2 diabetes, it is the first dual GIP and GLP-1 receptor agonist approved in the UK for weight management, setting it apart from other injectable treatments such as semaglutide (Wegovy), which targets GLP-1 alone. It received MHRA approval for this indication in November 2023. In December 2024, NICE recommended Mounjaro for NHS use, and it is now accessible through specialist weight management services in England.
Mounjaro works by mimicking two digestive hormones, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). These are the two main incretin hormones the intestines secrete when you consume sugar (glucose) or other nutrients that trigger insulin release.
By mimicking these hormones, Mounjaro helps promote weight loss by:
Mounjaro's dual mechanism gives it a broader metabolic reach than GLP-1-only treatments. While the GLP-1 component acts on appetite-regulating areas of the brain to reduce hunger and slow digestion, the GIP component improves how the body uses insulin, supports fat metabolism, and, when combined with GLP-1, appears to amplify its appetite-suppressing effects.
Together, these actions make it easier to eat less, manage blood sugar levels, and lose weight more effectively. Combined with lifestyle changes, this dual approach can lead to significant, sustained weight loss in suitable patients.
Mounjaro begins working within hours of the first injection, but noticeable changes take time to develop. Some people report reduced appetite within the first day or two, while others see gradual changes over one to two weeks. Visible weight loss typically follows in the weeks that follow, and it can take four to six months to see the full effects of treatment, reflecting the gradual dose increase. A post hoc analysis of the SURMOUNT-1 trial found that even among slower responders, the mean time to reach a 5% weight reduction was approximately 25 weeks, indicating that higher doses and longer-term use generally yield greater results.
It is important to have realistic expectations in the early weeks. Initial changes may be subtle, and some patients find appetite suppression becomes more consistent once tirzepatide levels stabilise after several doses. Staying committed to the recommended diet and exercise plan during this period supports the best possible outcome.
How much weight you can lose on Mounjaro depends on many factors, including how your body responds to tirzepatide and the lifestyle changes you make (such as eating a healthy diet or exercising regularly). Several clinical trials have studied potential Mounjaro results, including some that compared tirzepatide with other weight-loss injections such as Wegovy.
The SURMOUNT -3 trial studied Mounjaro's effect on weight loss in a double-blind, placebo-controlled design. After 12 weeks of intensive lifestyle intervention, participants who then received tirzepatide achieved a substantial average weight loss of 26.6% from study entry over 84 weeks. A further study, SURMOUNT-4, showed that over 88 weeks, people receiving tirzepatide (Mounjaro) lost an average of 26% of their body weight. The trial also found that withdrawing treatment led to weight gain, while continued treatment maintained weight loss.
Compared with semaglutide, the active ingredient in weight loss injections such as Wegovy, tirzepatide (Mounjaro) has been shown to produce greater weight loss. The SURMOUNT-5 head-to-head trial found that Mounjaro produced an average weight loss of 20.2% over 72 weeks, compared with 13.7% for Wegovy.

Weight loss takes time and effort, and you may not notice much change in the first few weeks of using Mounjaro. A study published in The New England Journal of Medicine (NEJM) shows that, in the first 4 weeks, weight loss can be gradual, but it increases with longer treatment. After 72 weeks, the average weight loss with a 5 mg once-weekly dose of Mounjaro was 16% (16.1 kg). At the highest dose of 15 mg once weekly, the mean weight loss was 23.6 kg.
Learning how to inject Mounjaro correctly is straightforward, and we want to make the process as easy as possible. You can watch our step-by-step video guide, or follow the detailed written instructions below.
Before injecting Mounjaro for the first time, you should first pick the day of the week you want to use it. Choose the same day each week. Set an alarm on your phone to remind you not to forget your Mounjaro day.
Once you have chosen your day, follow these simple steps:
If you’d like more detailed information about how to inject Mounjaro safely, please visit our dedicated guide.
The starting dose for Mounjaro weight loss injections is 2.5 mg once weekly for 4 weeks. After this point, our specialist clinicians will increase your dose to the next strength. This is provided your body has adjusted well to the potential side effects.
Throughout your weight loss journey, you will likely follow a Mounjaro dosing schedule that titrates up every 4 weeks until you reach the maintenance dose.
The Mounjaro dose chart is as follows:

Not everyone’s journey is the same. For example, you may choose a lower maintenance dose than 15 mg if you are happy with your results, or you may want to stay on your current dose longer if you are struggling with side effects. Additional considerations, such as age and existing medical conditions, will also influence how often you adjust the dose.
If you are switching to Mounjaro from another weight loss injection such as Wegovy, your starting dose may differ from the standard 2.5 mg. There is no direct dose conversion between the two medications, and your starting point will depend on your current dose, how well you have tolerated side effects, and how your treatment has been going.
Whatever your situation, our experienced clinicians will guide you through the process. More detailed information about the Mounjaro dosage schedule is available in our dedicated article.
You take Mounjaro once per week for four weeks using the Mounjaro KwikPen.
Consistency is important when taking Mounjaro. Taking your injection on the same day each week helps keep the medication working consistently, which supports appetite control and stable blood sugar levels. While the time of day is flexible, choose a time that fits your routine to stay on track. For more guidance on finding the right schedule for you, read our article on the best time of day to take Mounjaro.
Every four weeks, our clinicians will assess your progress and your tolerance to the current dose. They will advise you to either increase, decrease, or continue your current dose. To understand more about why dose increases are a normal and important part of the process, read our article on why you need to increase your Mounjaro dose.
If you have missed a Mounjaro dose and it has been:
You should never take a double dose to make up for a missed dose. Always wait at least 3 days between each Mounjaro dose.
Tirzepatide has a half-life of approximately five days, meaning it gradually clears from the body over time. Missing a dose may return your appetite sooner than usual, so maintaining a consistent weekly schedule is important for the best results.
If you have stopped taking Mounjaro for four weeks or more, you should not simply resume at your previous dose. Starting at a lower dose again gives your body time to readjust and reduces the risk of side effects. Our clinicians will advise you on the appropriate dose to restart on.
Taking too much Mounjaro is likely to cause an intensification of its usual side effects, particularly nausea and other gastrointestinal symptoms. There is no specific antidote, and treatment focuses on managing symptoms. Because tirzepatide stays active in the body for several days, any effects may last longer than expected. In rare cases, taking too much can lead to more serious complications, so if you experience severe or persistent vomiting, dizziness, or anything that concerns you, seek medical attention promptly.
Because Mounjaro weight loss injections are prescription-only, certain criteria must be met before you can receive treatment. Information about who can take Mounjaro is as follows:
We assess eligibility on an individual basis through our online consultation, which a qualified clinician reviews before issuing any prescription. In addition to meeting the BMI criteria above, we prescribe Mounjaro only as part of a broader weight management plan that includes a reduced-calorie diet and regular physical activity.
You can buy Mounjaro weight loss injections online from Prescription Doctor at the following prices:
Dose | Description | Price |
|---|---|---|
2.5mg | Starter | £169.99 |
5mg | Maintenance | £199.99 |
7.5mg | Maintenance | £249.99 |
10mg | Maintenance | £279.99 |
12.5mg | Maintenance | £289.99 |
15mg | Maintenance | £298.99 |
2.5 mg & 5 mg | Starter & Maintenance Bundle | £367.99 |
5 mg & 7.5 mg | Maintenance Bundle | £445.99 |
7.5 mg & 10 mg | Maintenance Bundle | £524.99 |
10 mg & 12.5 mg | Maintenance Bundle | £569.98 |
12.5 mg & 15 mg | Maintenance Bundle | £584.99 |
2 x 15 mg | Maintenance Bundle | £597.98 |
Remember, everyone’s weight loss journey is different, so you may achieve your desired results at a lower dose than the maximum of 15 mg per week. This means you could arrive at your maintenance dose sooner than 6 months. Our specialist clinicians are available to guide you through the process of finding the most suitable regimen for your circumstances.
Wegovy is a once-weekly injectable weight loss treatment manufactured by Novo Nordisk. It contains semaglutide, a GLP-1 receptor agonist, and is licensed in the UK for chronic weight management in eligible adults. Like Mounjaro, it is administered as a once-weekly subcutaneous injection and works by reducing appetite and slowing digestion.
The table below compares how much Wegovy and Mounjaro cost at Prescription Doctor:
| Month of Treatment | Mounjaro Price | Wegovy Price |
|---|---|---|
| Month 1 | £169.99 (2.5mg) | £109.99 (0.25mg) |
| Month 2 | £199.99 (5mg) | £119.99 (0.5mg) |
| Month 3 | £249.99 (7.5mg) | £139.99 (1mg) |
| Month 4 | £279.99 (10mg) | £164.99 (1.7mg) |
| Month 5 | £289.99 (12.5mg) | £184.99 (2.4mg) |
| Month 6 | £298.99 (15mg) | £249.99 (7.2mg) |
While Wegovy is more affordable, price alone shouldn't decide which weight loss injection to choose. The right treatment depends on your individual health profile, your weight loss goals, and how your body responds to medication. For a detailed breakdown of how the two treatments compare across effectiveness, side effects, and suitability, read our comprehensive Mounjaro vs Wegovy injections comparison.
As with all prescription medications, familiarise yourself with the possible side effects before you start treatment so you know what to watch for. This section covers the most common side effects associated with Mounjaro, including gastrointestinal symptoms such as nausea and diarrhoea, as well as the risk of hypoglycaemia and allergic reactions. It also outlines important warnings and interactions, including how Mounjaro may affect the contraceptive pill.
As with all medications, Mounjaro injections may cause side effects, though not everyone will experience them. It’s important to understand possible adverse effects before starting treatment so you can make an informed decision about whether Mounjaro suits your circumstances.
Potential Mounjaro side effects include:
Very Common (may affect more than 1 in 10 people) | Common (may affect up to 1 in 10 people) | Uncommon (may affect up to 1 in 100 people) |
|---|---|---|
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It’s important to note that this is not an exhaustive list of possible Mounjaro side effects. More information can be found within the Patient Information Leaflet.
Low blood sugar (hypoglycaemia) is a potential side effect of Mounjaro, and the risk varies depending on what other diabetes medications you are taking alongside it. According to the Mounjaro Patient Information Leaflet, hypoglycaemia is classified as:
If you are taking a sulphonylurea or insulin alongside Mounjaro, your doctor may need to reduce the dose of those medicines to lower your risk.
Symptoms of low blood sugar can include headache, drowsiness, weakness, dizziness, hunger, confusion, irritability, a rapid heartbeat, and sweating. Your doctor should tell you how to treat low blood sugar before you begin treatment.
Allergic reactions to Mounjaro can range in severity. For example, rashes, itching, or eczema are common Mounjaro side effects that could affect up to 1 in 10 users.
Severe allergic reactions to Mounjaro (such as an anaphylactic reaction and angioedema) are rare and could impact up to 1 in 1,000 people. You should seek immediate medical assistance if you experience symptoms such as:
Each Mounjaro KwikPen also contains Benzyl Alcohol, which may cause allergic reactions.
Although Mounjaro injections can be effective for weight loss, they are not suitable for everyone. The medication may not be safe for your personal circumstances or could interfere with other treatments that you’re taking. As a result, it’s important to clearly understand how Mounjaro may affect you before starting treatment.
Mounjaro is not suitable if you:
Before using Mounjaro for weight loss, please inform our clinicians if you:
Stop using Mounjaro and seek urgent medical help if you develop severe, persistent stomach pain, with or without nausea and vomiting, as this may be a sign of acute pancreatitis. More information about potential interactions between tirzepatide and other medications is available in our guide.
While taking Mounjaro, you may experience sickness and/or diarrhoea, which can cause dehydration if you don’t drink enough fluids. Drink plenty of water when using Mounjaro weight loss injections.
If you’re taking contraceptive pills, Mounjaro may reduce their effectiveness. Because of this, it’s recommended that you use a non-oral form of contraception (such as condoms) in addition to your usual method for 4 weeks after you start Mounjaro treatment, and then for 4 weeks after each dose increase.
Mounjaro may interact with several other medications. Please inform our clinicians of everything you are currently taking before starting treatment
Mounjaro should not be used during pregnancy, as the effects of tirzepatide on an unborn child are not known. If you are pregnant, think you may be pregnant, or are planning to have a baby, you should not start Mounjaro treatment and should speak to your doctor for advice. It is recommended that you use contraception while using Mounjaro.
Tirzepatide passes into breast milk in very small amounts and is not expected to be absorbed by a breastfed newborn or infant. If you are breastfeeding or planning to do so, speak to your doctor before using or continuing this medicine.
For more detailed information, read our dedicated guide on Mounjaro and pregnancy.
Mounjaro is a prescription-only medication, so you can't get it without a valid prescription from a qualified clinician. In the UK, eligible patients can access it through the NHS and regulated private providers. The right route for you will depend on your circumstances, including whether you meet the current NHS eligibility criteria and how quickly you need to start treatment.
No. Mounjaro is a prescription-only medication and cannot be purchased over the counter in the UK. It must be prescribed by a qualified clinician following an assessment of your eligibility. Buying Mounjaro from unregulated sources is unsafe and illegal. Always ensure you obtain treatment through a registered pharmacy or regulated online provider.
Yes, though access is currently limited. NICE approved Mounjaro for treating obesity on the NHS in December 2024, and it is now available through specialist weight management services in England, with some GP access for those with the greatest clinical need. If you don't currently qualify or face a lengthy wait, Prescription Doctor offers Mounjaro privately for those who meet the prescribing criteria.
Yes, you can buy Mounjaro online in the UK from regulated and reputable pharmacies such as Prescription Doctor. Our process is extremely straightforward, with no need for an appointment. Complete a brief medical questionnaire, and our experienced clinicians will determine whether the medication is suitable for your circumstances.
If approved, your treatment will be dispatched by our General Pharmaceutical Council-registered pharmacy in plain packaging for total discretion. Orders approved before 3pm Monday to Friday are also eligible for next-day delivery. Our process is a convenient way to beat NHS waiting lists, and you could start treatment the very next day. We also include guides to essential information, such as diet plans (vegan and non-vegan), foods to avoid, and vitamins you could take, as part of our service.
Yes, several Mounjaro alternatives for weight loss are available if you think tirzepatide may not be suitable for you. You may even be uncomfortable with the idea of self-injecting, so weight loss pills may be a better option.
At Prescription Doctor, we offer the following treatments as alternatives to Mounjaro:
If you’re unsure which treatment suits your circumstances, our clinicians will be happy to help.
Yes. Mounjaro's approval for weight management was based on two international, randomised, double-blind, placebo-controlled clinical trials (SURMOUNT-1 and SURMOUNT-2), and the MHRA will continue to closely review its safety. As with all prescription medications, it can cause side effects, and it is not suitable for everyone.
Before starting treatment, our clinicians will assess your eligibility and medical history to ensure Mounjaro is appropriate for your circumstances.
The UK Medicines and Healthcare Regulatory Agency (MHRA) first licensed Mounjaro for weight loss in November 2023. A further licence for the Mounjaro KwikPen was issued in January 2024. The aim of this was to “enable access to the approved Mounjaro pen in a more convenient presentation”.
There is no official guidance saying you cannot drink alcohol while taking Mounjaro, and the occasional drink is unlikely to cause harm. That said, both alcohol and Mounjaro slow digestion, which can make nausea and other stomach side effects worse. Alcohol is also high in calories, which can undermine your progress.
If you do drink, try to keep within the NHS-recommended guidelines of no more than 14 units per week. It is worth being extra cautious if you are also taking diabetes medications such as sulphonylureas or insulin, as the combination can increase the risk of low blood sugar. If you are unsure, have a chat with your clinician.
After your last injection, Mounjaro remains active in your body for around 25 to 30 days, gradually clearing over that period. This means effects like reduced appetite may continue for a week or two after you stop.
If you miss a dose, Mounjaro does not simply stop working overnight. A meaningful amount of the medication will still be active in your body, so the guidance allows you to take a missed dose up to four days late. If you are stopping treatment altogether, talk to your clinician first, especially if you are considering switching to another medication, since the overlap period is worth factoring in.
You can inject Mounjaro into the stomach, thigh, or back of the upper arm, and clinical studies show absorption is broadly comparable across all three sites. In practice, the best injection site is whichever you find most comfortable and easiest to access each week consistently.
What matters more than the specific site is rotating your injection within that area each week. Using the same spot repeatedly can cause skin changes that may affect absorption over time. For more detailed guidance on technique and site selection, take a look at our article on Mounjaro injection sites.
Store unopened Mounjaro KwikPens in the fridge between 2°C and 8°C until you are ready to use them. Once you start using a pen, you can keep it at room temperature below 30°C for up to 30 days, after which you must discard it. Keep the pen in its original carton to protect it from light, and store it out of the reach of children.
Never freeze your Mounjaro pen. If it has been frozen at any point, it must not be used. Before injecting, check that the solution is clear and colourless to slightly yellow. If it appears cloudy, discoloured, or contains particles, do not use it and contact your pharmacist. Remember to remove the needle after each injection and replace the pen cap, as storing the pen with a needle attached can cause air bubbles to form, which may affect dose accuracy.
The clinical evidence is compelling. In the SURMOUNT trials, participants lost an average of 15% to 22.5% of their body weight, depending on the dose, among the strongest results observed with any licensed weight-loss treatment. When combined with a reduced-calorie diet and regular physical activity, Mounjaro has been shown to produce meaningful, sustained weight loss in suitable patients.
Of course, results vary from person to person, and individual factors such as starting weight, diet, activity levels, and how well you tolerate dose increases will all play a role. To see what real patients have experienced, check out our Mounjaro reviews.
If Mounjaro doesn't seem to be working, consider whether you are on an optimal dose, maintaining a reduced-calorie diet, and injecting each week consistently. Progress can also slow at various points, particularly in the earlier weeks of treatment. Individual factors such as underlying health conditions may also play a role.
Our articles on why Mounjaro may not be working and Mounjaro tips and tricks explore this in more detail. If you have ongoing concerns, speak to your clinician, who can review your progress and advise on next steps.
On average, yes - though both are effective treatments. The SURMOUNT-5 trial, a direct head-to-head comparison, found that Mounjaro resulted in an average weight loss of 20.2% at 72 weeks, compared with 13.7% with Wegovy. Mounjaro's dual GIP and GLP-1 mechanism is thought to contribute to these stronger results.
That said, the best treatment is the one that works for you individually. Side effect profiles, tolerability, and cost all vary between the two, and some people respond better to one than the other. For a detailed breakdown, read our comprehensive Mounjaro vs Wegovy comparison.
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