Mounjaro Before and After: Weight Loss Success Stories

Weight loss is undoubtedly a personal process. It’s different for everyone, and people have different aims – from gaining confidence to re-discovering old and new activities, playing more with their children or grandchildren, or simply reclaiming overall health.

Mounjaro (tirzepatide) has become something of a lifeline for many attempting to lose weight in the long term. It can offer that all-important boost to your efforts, supporting your weight loss objectives while improving overall health.

There’s no better way to understand Mounjaro’s potential benefits than by exploring stories from real people who used this medication to change their lives for the better, which is what we’ll do here.

What Is Mounjaro and How Does It Work? A Quick Recap

Let’s very quickly recap Mounjaro and how it works. Originally developed to treat type 2 diabetes, Mounjaro has proven highly effective in helping people lose weight and keep it off for the long term.

It works by mimicking two key hormones – GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) – which play a role in blood sugar control and satiety (fullness after eating).

By activating these receptors, Mounjaro helps reduce hunger, slows the emptying of food from the stomach, and enhances the body's ability to manage glucose levels, ultimately leading to sustained weight loss.

Without further discussion, let’s review ten real Mounjaro weight loss stories and the people behind them.

User 1: 82 Pounds (37.2 kg) Down in 16 Months

• Starting Weight: 254 lbs (115.2 kg)
• Current Weight: 172 lbs (78.0 kg)
• Time Using Mounjaro/Wegovy: 1 year, 4 months
• Dosage: Gradual increases
• Total Weight Loss: 82 lbs (37.2 kg)

Over 16 months, this user lost 82 pounds (37.2 kg), steadily working their way down from 254 lbs to 172 lbs. They started Mounjaro on November 15, 2022, before switching to Wegovy. With consistent effort, they steadily reached a much healthier weight and maintained their progress for a sizeable duration.

User 2: 203 Pounds (92 kg) Down in Under Two Years

• Starting Weight: 423 lbs (191.9 kg)
• Current Weight: 220 lbs (99.8 kg)
• BMI Change: 51.5 to 26.8
• Time Using Mounjaro: 1 year, 8 months
• Total Weight Loss: 203 lbs (92 kg)

For this user, Mounjaro saw them drop from a BMI of 51.5 – well into the “severely obese” range – to 26.8, an outstanding improvement in less than two years. They improved their diet with lean protein and vegetables, with sugar-free gummy bears to manage cravings.

User 3: 85 Pounds (38.5 kg) Down in 1 Year, 3 Months

• Starting Weight: Not specified
• Current Weight: Not specified
• Time Using Mounjaro: 1 year, 3 months
• Dosage: Max 7.5 mg
• Total Weight Loss: 85 lbs (38.5 kg)

This user started Mounjaro in December 2022 with insulin resistance, high blood pressure, and elevated cholesterol levels. By September 2023, they had lost 50 lbs (22.7 kg). Over the next six months, they lost another 35 lbs (15.9 kg), maintaining their progress since March 2024. Staying at 7.5 mg, they attempted 10 mg but found it intolerable. Now off all other medications, their lab results are within normal limits.

User 4: 21 Pounds (9.5 kg) Down in 5 Weeks

• Starting Weight: 23.5 st (329 lbs / 149.2 kg)
• Current Weight: 22 st (308 lbs / 139.7 kg)
• Time Using Mounjaro: 5 weeks
• Dosage: 5 mg
• Total Weight Loss: 21 lbs (9.5 kg)

After starting Mounjaro at 23.5 stone (329 lbs), this user has already lost 1.5 stone (21 lbs / 9.5 kg) in just five weeks. Before starting Mounjaro, they had already begun losing weight, but it was vastly accelerated since beginning the medication. Alongside pole fitness, gym sessions, and walking, they’ve completely overhauled their diet, finding that Mounjaro helps reduce cravings and improve food choices. Now on 5 mg, they feel more confident and motivated – well on the right path to long-term weight loss.

User 5: One Year, 88 Pounds (39.9 kg) Down

• Starting Weight: 214.8 lbs (97.4 kg)
• Current Weight: 126.8 lbs (57.5 kg)
• Time Using Mounjaro: 1 year
• Dosage: Not specified
• Total Weight Loss: 88 lbs (39.9 kg)

Over the past year, this user lost a massive 88 pounds (39.9 kg), reaching their goal weight. They focused on simple, repetitive meals instead of complex meal planning, which had previously made dieting difficult. Exercise via an exercise bike supported their motivation. Now, in maintenance, they’re staying consistent and maintaining the dieting state of mind but with a little flexibility.

If you’re thinking about trying Mounjaro yourself, you’ll need a prescription – Prescription Doctor offers a straightforward online consultation to get started.

User 6: 47 Pounds (21.4 kg) Down in Just 3 Months

• Starting Weight: 251.6 lbs (114.1 kg)
• Current Weight: 204.5 lbs (92.8 kg)
• Target Weight: 190 lbs (86.2 kg)
• Time Using Mounjaro: 3 months
• Dosage: 5 mg
• Total Weight Loss: 47.1 lbs (21.4 kg)

This former athlete struggled with weight gain post-career, dealing with chronic joint pain, multiple knee surgeries, and gout. In just 90+ days on Mounjaro, they dropped 47 lbs (21.3 kg), going from 251.6 lbs (114.1 kg) to 204.5 lbs (92.8 kg). They revamped their diet and lifestyle, ditching carbs, sugar, and alcohol, focusing on single-ingredient foods – and adding plenty of walking to their routine. It’s an incredibly strong start in a short space of time.

User 7: 34 Pounds (15.4 kg) Down

• Starting Weight: 215 lbs (97.5 kg)
• Current Weight: 181 lbs (82.1 kg)
• Target Weight: 137 lbs (62.1 kg)
• Time Using Mounjaro: Not specified
• Dosage: 7.5 mg
• Total Weight Loss: 34 lbs (15.4 kg)

Since starting Mounjaro, this user lost 34 lbs (15.4 kg), going from 215 lbs (97.5 kg) to 181 lbs (82.1 kg). Their first picture was taken two months postpartum, and the second was from their most recent update. With steady progress, they were ready to start shopping for new clothes.

You can achieve similar results by starting our online Mounjaro consultation. Our professional, regulated pharmacists will assess your information to determine whether you’re a good candidate for the medication.

User 8: 60 Pounds (27 kg) Down and Maintaining

• Starting Weight: Not specified
• Current Weight: Not specified
• Time Using Mounjaro: 2 years
• Dosage: 15 mg for 1.5 years
• Total Weight Loss: 60 lbs (27.2 kg)

After two years on Mounjaro, this user lost 60 pounds (27.2 kg) in the first year and maintained their weight throughout the second. They had been on 15 mg for the past 1.5 years and continued feeling good with their results.

User 9: 95 Pounds (43 kg) Down in Just 6 Months

• Starting Weight: 144 kg (317 lbs)
• Current Weight: 101 kg (222 lbs)
• Time Using Mounjaro: 6 months
• Dosage: Not specified
• Total Weight Loss: 43 kg (95 lbs)

Between May and November, this user lost 40 kg (88 lbs), dropping from 144 kg to 104 kg. After taking a break from dieting while travelling, they were surprised to maintain their weight – something that had never happened before. After returning home, they got back on track and dropped another 3 kg (6.6 lbs), bringing their total weight loss to a brilliant 43 kg (95 lbs).

User 10: An Outstanding Start in 6 Months

• Starting Weight: 250 lbs (113.4 kg)
• Current Weight: 213 lbs (96.6 kg)
• Time Using Mounjaro: 6 months
• Dosage: Not specified
• Total Weight Loss: 37 lbs (17 kg)

Over 6 months on Mounjaro, this user lost 37 pounds (17 kg), going from 250 lbs (113.4 kg) to 213 lbs (96.6 kg). Before starting, they struggled with pain, mobility issues, IBS, and GERD. Now, they could move more easily, run up and down stairs, and observe major improvements in skin, mood, and overall health.

Closing Thoughts

Mounjaro experiences are diverse. While there’s some incredible weight loss among these stories, you’ve got to be prepared to commit to lifestyle changes to receive the full benefits of this medication.

It’s always worth remembering that the medication works best as part of a combined effort to improve your health. Balanced meals, physical activity, and regular check-ins with your doctor or pharmacist are all key pieces of the puzzle.

At Prescription Doctor, we offer Mounjaro via an online consultation. Getting started is simple, simply start your consultation. You'll complete a short online assessment, which one of our licensed providers will review. If approved, your prescription will be sent directly to you.

We provide the full range of Mounjaro dosages – 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15mg – so you can start at the right level and adjust as needed over time.

If you have any questions, we're here to help. Get in touch, and we’ll guide you through the process.

Authored & Reviewed By

Mohamed Imran Lakhi

MPharm - Lead Pharmacist

Imran Lakhi is the superintendent pharmacist and founder at Prescription Doctor. He has been at the core of our team.

Published on: 07/02/2025 Reviewed on: 07/02/2025